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A systematic survey of LU domain-containing proteins reveals a novel human gene, LY6A, which encodes
Frontiers of Medicine 2023, Volume 17, Issue 3, Pages 458-475 doi: 10.1007/s11684-022-0968-4
Keywords: LU domain-containing protein family novel human gene LY6A pituitary tumor biomarker nonsynonymous
The antibiotic resistome: gene flow in environments, animals and human beings
Yongfei Hu, George F. Gao, Baoli Zhu
Frontiers of Medicine 2017, Volume 11, Issue 2, Pages 161-168 doi: 10.1007/s11684-017-0531-x
The antibiotic resistance is natural in bacteria and predates the human use of antibiotics.However, the antibiotic selection pressure conferred by the use of antibiotics in both human medicineregarding the collective ARGs (antibiotic resistome) in bacterial communities of natural environments, humanWe propose that the resistance gene flow in nature is “from the natural environments” and, contribute greatly to such a resistance gene “circulation.
Keywords: antibiotic resistance resistome microbiome gene flow
Lu Wang
Frontiers of Medicine 2013, Volume 7, Issue 3, Pages 280-289 doi: 10.1007/s11684-013-0265-3
Many gene fusions have been recognized as important diagnostic and/or prognostic markers in humanIn recent years, novel gene fusions have been identified in cases without prior knowledge of the geneticThis review focused on advanced genome-wide screening approaches in fusion gene identification, suchas microarray-based approaches, next-generation sequencing, and NanoString nCounter gene expression systemThe fundamental rationale and strategy for fusion gene identification using each biotech platform are
Keywords: gene fusion cancer microarray next-generation sequencing NanoString nCounter system
A novel variant in the gene in a large Chinese family with a unique phenotype of Clouston syndrome
Frontiers of Medicine 2023, Volume 17, Issue 2, Pages 330-338 doi: 10.1007/s11684-022-0933-2
Keywords: Clouston syndrome whole exome sequencing GJB6 gene novel variant unique phenotype
Optimized human factor IX expression cassettes for hepatic-directed gene therapy of hemophilia B
Ru Zhang,Qiang Wang,Lin Zhang,Saijuan Chen
Frontiers of Medicine 2015, Volume 9, Issue 1, Pages 90-99 doi: 10.1007/s11684-015-0390-2
Gene therapy provides a potential cure for hemophilia B, and significant progress has been achievedin liver-directed gene transfer mediated by adeno-associated viral vectors.Recent clinical trials involving the use of a self-complementary adeno-associated virus serotype 8-humanvectors and hFIX expression cassette may positively contribute to the ultimate success of hemophilia B geneto obtain a higher expression level of hFIX that potentiates the coagulant capacity of recipients, human
Keywords: factor IX hemophilia B liver-specific regulatory elements hydrodynamic gene transfer
Antitumor immunity of human SART3 gene vaccine against mouse tumor
HE Yu, YANG Shuhua, LIU Yong, LI Tao
Frontiers of Medicine 2008, Volume 2, Issue 1, Pages 51-57 doi: 10.1007/s11684-008-0010-5
Keywords: antitumor therapy occurrence implantation DNA vaccine SART3 DNA
Compiling of comprehensive data of human infections with novel influenza A (H7N9) virus
Ying Wu, George F. Gao
Frontiers of Medicine 2013, Volume 7, Issue 3, Pages 275-276 doi: 10.1007/s11684-013-0285-z
a novel K+ transporter gene in cotton
Yiru WANG, Juan XU, Mingcai ZHANG, Xiaoli TIAN, Zhaohu LI
Frontiers of Agricultural Science and Engineering 2018, Volume 5, Issue 2, Pages 226-235 doi: 10.15302/J-FASE-2017170
Keywords: cotton GhKT2 potassium transporter uptake
A novel aldo-keto reductase gene,
Jinxi HUO, Bing DU, Sifan SUN, Shaozhen HE, Ning ZHAO, Qingchang LIU, Hong ZHAI
Frontiers of Agricultural Science and Engineering 2018, Volume 5, Issue 2, Pages 206-213 doi: 10.15302/J-FASE-2018225
Keywords: cadmium stress IbAKR Ipomoea batatas sweet potato
Xia Jiahui
Strategic Study of CAE 2000, Volume 2, Issue 11, Pages 1-11
In this paper, the study on family collection, gene mapping, gene identification and gene functionof human genetic diseases carried out in the National Laboratory of Medical Genetics of China, werechromosome t (1; 3) (q44; p11) associated with nasopharyngeal cancer was found in 1975 at first, and humanIn 1998, GJB3, a human genetic neurological deafness gene, was identified using a novel strategy of &actinic porokeratosis (DSAP) was identified at Chromosome 12q23. 2 - 24. 1; and at the same year a novel
Keywords: genetic disease gene mapping and cloning gene familiy-candidate disease gene cloning genome wide scan gene function study
662 A/G gene variation in human tumor necrosis factor receptor superfamily, member 9 (TNFRSF9)
QU Yanchun, YANG Ze, SUN Liang, JI Linong
Frontiers of Medicine 2008, Volume 2, Issue 3, Pages 283-285 doi: 10.1007/s11684-008-0053-7
Keywords: D-HPLC mutation development autoimmune PCR-RFLP candidate
Expression and bioinformatic analysis of lymphoma-associated novel gene KIAA0372
BAI Xiangyang, TANG Duozhuang, ZHU Tao, SUN Lishi, YAN Lingling, LU Yunping, ZHOU Jianfeng, MA Ding
Frontiers of Medicine 2007, Volume 1, Issue 1, Pages 93-98 doi: 10.1007/s11684-007-0018-2
Keywords: bioinformatic analysis functional KIAA0372 detection Microarray
Genetic Study Identifies CBLN4 as a Novel Susceptibility Gene for Accident Proneness
Shu-lin Zhang,Hui-qing Jin,Yang Song,Wan-sheng Yu,Liang-dan Sun
Frontiers of Engineering Management 2016, Volume 3, Issue 1, Pages 30-38 doi: 10.15302/J-FEM-2016008
Keywords: accident proneness genome-wide association study (GWAS) dopamine (DA) ACTH susceptibility gene traffic
Qiong CHEN, Qing YU, Yuhu SONG, Peiyuan Li, Ying CHANG, Zhijun WANG, Lifeng LIU, Wei WU, Jusheng LIN
Frontiers of Medicine 2009, Volume 3, Issue 2, Pages 148-152 doi: 10.1007/s11684-009-0032-7
Keywords: gene X-linked inhibitor of apoptosis protein associated factor-1 (XAF1) promoter transcription regulation
Frontiers of Medicine 2022, Volume 16, Issue 4, Pages 584-595 doi: 10.1007/s11684-021-0844-7
Keywords: hemophilia A adeno-associated virus (AAV) human/rat hybrid factor VIII gene therapy dual chain strategy
Title Author Date Type Operation
A systematic survey of LU domain-containing proteins reveals a novel human gene, LY6A, which encodes
Journal Article
The antibiotic resistome: gene flow in environments, animals and human beings
Yongfei Hu, George F. Gao, Baoli Zhu
Journal Article
Identification of cancer gene fusions based on advanced analysis of the human genome or transcriptome
Lu Wang
Journal Article
A novel variant in the gene in a large Chinese family with a unique phenotype of Clouston syndrome
Journal Article
Optimized human factor IX expression cassettes for hepatic-directed gene therapy of hemophilia B
Ru Zhang,Qiang Wang,Lin Zhang,Saijuan Chen
Journal Article
Antitumor immunity of human SART3 gene vaccine against mouse tumor
HE Yu, YANG Shuhua, LIU Yong, LI Tao
Journal Article
Compiling of comprehensive data of human infections with novel influenza A (H7N9) virus
Ying Wu, George F. Gao
Journal Article
a novel K+ transporter gene in cotton
Yiru WANG, Juan XU, Mingcai ZHANG, Xiaoli TIAN, Zhaohu LI
Journal Article
A novel aldo-keto reductase gene,
Jinxi HUO, Bing DU, Sifan SUN, Shaozhen HE, Ning ZHAO, Qingchang LIU, Hong ZHAI
Journal Article
Study on Family Collection, Gene Mapping, Gene Identification and Gene Function of Human Genetic Diseases
Xia Jiahui
Journal Article
662 A/G gene variation in human tumor necrosis factor receptor superfamily, member 9 (TNFRSF9)
QU Yanchun, YANG Ze, SUN Liang, JI Linong
Journal Article
Expression and bioinformatic analysis of lymphoma-associated novel gene KIAA0372
BAI Xiangyang, TANG Duozhuang, ZHU Tao, SUN Lishi, YAN Lingling, LU Yunping, ZHOU Jianfeng, MA Ding
Journal Article
Genetic Study Identifies CBLN4 as a Novel Susceptibility Gene for Accident Proneness
Shu-lin Zhang,Hui-qing Jin,Yang Song,Wan-sheng Yu,Liang-dan Sun
Journal Article
Cloning of human XAF1 gene promoter and assay of its transcription activity in a variety of cell lines
Qiong CHEN, Qing YU, Yuhu SONG, Peiyuan Li, Ying CHANG, Zhijun WANG, Lifeng LIU, Wei WU, Jusheng LIN
Journal Article